top of page


Here is a brief insight into genetic issues within the Cavapoo and Toy Poodle that we test for at Prestige Cavapoo. Some dogs are tested for more than others depending on their parents testing history and their breed and all copies of our dogs CLEAR results will be available for you to see when you visit us. No dogs are ever bred from that are tested and are found to be at risk of any of these conditions.

Congenital Macrothrombocytopaenia

  • What is Congenital Macrothrombocytopenia?

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or number of their platelets, but their reduced number of platelets on a routine blood panel can be concerning. As such, dogs with inherited macrothrombocytopenia are often unnecessarily subjected to a number of diagnostic tests and medications to rule out an underlying cause of their macrothrombocytopenia, including diseases of infectious, inflammatory, autoimmune, or toxic origins.

Degenerative Myelopathy (DM)

  • Canine degenerative myelopathy, also known as chronic degenerative radiculomyelopathy, is an incurable, progressive disease of the canine spinal cord that is similar in many ways to amyotrophic lateral sclerosis.

Curly Coat Dry Eye (CCDE)

  • Curly Coat Dry Eye Syndrome, also known as Congenital Keratoconjunctivitis Sicca and Ichthyosiform Dermatosis, is an autosomal recessive disorder that affects King Charles Spaniels. This genetic disorder is best characterized by an abnormally rough or curly coat at birth with extreme cases of dry eye as the puppy matures.

Episodic Falling (EF)

  • Description: Episodic Falling (EF) is an autosomal recessive disorder predominantly found in King Charles Spaniels. It is characterized by muscle stiffness and collapse of the dog during times of excitement, stress, or exercise. Episodes can last for several seconds or several minutes.

Gangliosidosis (GM2)

  • What is GM2? An early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young adults. These include partial or total vision loss, behavior changes, abnormal gait, and seizures.


Osteochondrodysplasia (OCD)

  • Osteochondrodysplasia is characterized by stunted growth and abnormal locomotion. Affected animals develop splayed hind limbs, enlarged joints, flattened rib cages, shortened and bent long bones, and deformed paws. Phenotype: Osteochondrodysplasia is characterized by stunted growth and abnormal locomotion.

Progressive Retinal Atrophy (PRA-PRCD)

  • Progressive Rod-Cone Degeneration, or PRA-prcd, is a form of Progressive Retinal Atrophy (PRA) in which the cells in the dog's retina degenerate and die. PRA for dogs is similar to retinitis pigmentosa in humans. Most affected dogs will not show signs of vision loss until 3-5 years of age.

Von Willebrand Disease I (vWD1)

  • Von Willebrand's disease (vWD) is the most common inherited bleeding disorder of both humans and dogs. It is caused by a deficiency in the amount of a specific protein needed to help platelets (the blood cells used in clotting) stick together and form clots to seal broken blood vessels. The deficient protein is called von Willebrand factor (vWF).

Progressive Retinal Atrophy (PRA-rcd4)

  • PRA-rcd4 (progressive retinal atrophy rod-cone degeneration 4) is a late-onset PRA mutation that causes bilateral degeneration of the retina which causes progressive vision loss, and eventually blindness.

Genetic Health Testing: About
bottom of page