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HEALTH AND GENETIC TESTING

Here is a brief insight into genetic issues within the Cavapoo and Toy Poodle that we test for at Prestige Cavapoo. Some dogs are tested for more than others depending on their parents testing history and their breed and all copies of our dogs CLEAR results will be available for you to see when you visit us. No dogs are ever bred from that are tested and are found to be at risk of any of these conditions.

Congenital Macrothrombocytopaenia

  • What is Congenital Macrothrombocytopenia?

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or number of their platelets, but their reduced number of platelets on a routine blood panel can be concerning. As such, dogs with inherited macrothrombocytopenia are often unnecessarily subjected to a number of diagnostic tests and medications to rule out an underlying cause of their macrothrombocytopenia, including diseases of infectious, inflammatory, autoimmune, or toxic origins.


Degenerative Myelopathy (DM)

  • Canine degenerative myelopathy, also known as chronic degenerative radiculomyelopathy, is an incurable, progressive disease of the canine spinal cord that is similar in many ways to amyotrophic lateral sclerosis.


Curly Coat Dry Eye (CCDE)

  • Curly Coat Dry Eye Syndrome, also known as Congenital Keratoconjunctivitis Sicca and Ichthyosiform Dermatosis, is an autosomal recessive disorder that affects King Charles Spaniels. This genetic disorder is best characterized by an abnormally rough or curly coat at birth with extreme cases of dry eye as the puppy matures.


Episodic Falling (EF)

  • Description: Episodic Falling (EF) is an autosomal recessive disorder predominantly found in King Charles Spaniels. It is characterized by muscle stiffness and collapse of the dog during times of excitement, stress, or exercise. Episodes can last for several seconds or several minutes.

Gangliosidosis (GM2)

  • What is GM2? An early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young adults. These include partial or total vision loss, behavior changes, abnormal gait, and seizures.

            

Osteochondrodysplasia (OCD)

  • Osteochondrodysplasia is characterized by stunted growth and abnormal locomotion. Affected animals develop splayed hind limbs, enlarged joints, flattened rib cages, shortened and bent long bones, and deformed paws. Phenotype: Osteochondrodysplasia is characterized by stunted growth and abnormal locomotion.


Progressive Retinal Atrophy (PRA-PRCD)

  • Progressive Rod-Cone Degeneration, or PRA-prcd, is a form of Progressive Retinal Atrophy (PRA) in which the cells in the dog's retina degenerate and die. PRA for dogs is similar to retinitis pigmentosa in humans. Most affected dogs will not show signs of vision loss until 3-5 years of age.


Von Willebrand Disease I (vWD1)

  • Von Willebrand's disease (vWD) is the most common inherited bleeding disorder of both humans and dogs. It is caused by a deficiency in the amount of a specific protein needed to help platelets (the blood cells used in clotting) stick together and form clots to seal broken blood vessels. The deficient protein is called von Willebrand factor (vWF).


Progressive Retinal Atrophy (PRA-rcd4)

  • PRA-rcd4 (progressive retinal atrophy rod-cone degeneration 4) is a late-onset PRA mutation that causes bilateral degeneration of the retina which causes progressive vision loss, and eventually blindness.

When we have bought puppies that are to be used in our breeding programs when they mature, we have bought them in good faith from the breeders we chose hoping that they have been honest with all aspects of the puppy and that we have chose correctly. Its always difficult to find a good breeder and even more so with a crossbreed  but we couldn't be happier with our little herd. All happy, healthy pooches!

However when it comes to health this is the most important factor for us when breeding which is why we health test our breeding dogs before we decide to breed them despite of any parentage health tests we have been given and we do this for our own peace of mind. Of course there are many other things that can go wrong with any dogs health but we hope we have done enough to eradicate these potential issues from the puppies we produce. 

Genetic Health Testing: About
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